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Californium-252 plasma desorption mass analysis of proteins adsorbed on polymer and modified-polymer surfaces
| dc.contributor.advisor | Macfarlane, R. D. | |
| dc.creator | Hill, John Chester | |
| dc.date.accessioned | 2020-09-02T21:10:45Z | |
| dc.date.available | 2020-09-02T21:10:45Z | |
| dc.date.issued | 1987 | |
| dc.identifier.uri | https://hdl.handle.net/1969.1/DISSERTATIONS-754066 | |
| dc.description | Typescript (photocopy). | en |
| dc.description.abstract | A new Cf-252 plasma desorption mass spectrometer has been built specifically for the analysis of large biomolecules. This mass spectrometer was used to investigate the interactions between proteins adsorbed onto polymer surfaces and how the chemical nature of the polymer surface influences the production of stable, gas-phase molecular ions. Chemical modification of the polymer surfaces was achieved by means of ultra-violet irradiation, resulting in the production of a more hydrophilic surface. Analysis of a series of model compounds adsorbed onto modified and non-modified polymer surfaces indicates that the wettability of the surface is an important influence in the production of stable molecular ions. This information was then utilized to aid in the analysis of lysozyme, myoglobin, and porcine trypsin. | en |
| dc.format.extent | xiv, 243 leaves | en |
| dc.format.medium | electronic | en |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | eng | |
| dc.rights | This thesis was part of a retrospective digitization project authorized by the Texas A&M University Libraries. Copyright remains vested with the author(s). It is the user's responsibility to secure permission from the copyright holder(s) for re-use of the work beyond the provision of Fair Use. | en |
| dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | |
| dc.subject | Major chemistry | en |
| dc.subject.classification | 1987 Dissertation H646 | |
| dc.subject.lcsh | Plasma desorption mass spectrometry | en |
| dc.subject.lcsh | Proteins | en |
| dc.subject.lcsh | Absorption and adsorption | en |
| dc.title | Californium-252 plasma desorption mass analysis of proteins adsorbed on polymer and modified-polymer surfaces | en |
| dc.type | Thesis | en |
| thesis.degree.discipline | Chemistry | en |
| thesis.degree.grantor | Texas A&M University | en |
| thesis.degree.name | Doctor of Philosophy | en |
| thesis.degree.name | Ph. D. in Chemistry | en |
| thesis.degree.level | Doctorial | en |
| dc.contributor.committeeMember | Naugle, D. G. | |
| dc.contributor.committeeMember | Russell, D. H. | |
| dc.contributor.committeeMember | Schweikert, E. A. | |
| dc.type.genre | dissertations | en |
| dc.type.material | text | en |
| dc.format.digitalOrigin | reformatted digital | en |
| dc.publisher.digital | Texas A&M University. Libraries | |
| dc.identifier.oclc | 18928194 |
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