NOTE: This item is not available outside the Texas A&M University network. Texas A&M affiliated users who are off campus can access the item through NetID and password authentication or by using TAMU VPN. Non-affiliated individuals should request a copy through their local library's interlibrary loan service.
Tissue culture as a means of establishing an epidermal-implant union in percutaneous implants
dc.contributor.advisor | Tiffany-Castiglioni, E. | |
dc.creator | Clarkson, Christina Rothen | |
dc.date.accessioned | 2020-08-21T21:45:20Z | |
dc.date.available | 2020-08-21T21:45:20Z | |
dc.date.issued | 1985 | |
dc.identifier.uri | https://hdl.handle.net/1969.1/DISSERTATIONS-445971 | |
dc.description | Typescript (photocopy). | en |
dc.description.abstract | Tissue culture was used as a method for establishing an epidermal union to the polycarbonate flange of a percutaneous implant. The cells united to the implant material in culture as indicated by the formation of hemidesmosomes in close association with the polycarbonate. Rat tail collagen coated on the polycarbonate facilitated the attachment of epidermal cells to this material. By seven days the cells covered the surface of the implant flange when innoculated at a high seed density. When a low number of cells was used to initiate a culture, epidermal growth factor and/or brain extract were required to bring the culture to confluence. A sheet of transplanted cultured epidermal cells showed evidence of intact cells at 48 hours. The implant with cultured epidermal cells failed to unite with the tissues of the graft bed and the cells deteriored. Therefore, the model tested was not a successful percutaneous implant. | en |
dc.format.extent | vii, 104 leaves | en |
dc.format.medium | electronic | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | |
dc.rights | This thesis was part of a retrospective digitization project authorized by the Texas A&M University Libraries. Copyright remains vested with the author(s). It is the user's responsibility to secure permission from the copyright holder(s) for re-use of the work beyond the provision of Fair Use. | en |
dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | |
dc.subject | Major veterinary anatomy | en |
dc.subject.classification | 1985 Dissertation C613 | |
dc.subject.lcsh | Implants, Artificial | en |
dc.subject.lcsh | Tissue culture | en |
dc.title | Tissue culture as a means of establishing an epidermal-implant union in percutaneous implants | en |
dc.type | Thesis | en |
thesis.degree.grantor | Texas A&M University | en |
thesis.degree.name | Doctor of Philosophy | en |
thesis.degree.name | Ph. D | en |
dc.contributor.committeeMember | Hobson, H. P. | |
dc.contributor.committeeMember | Hyman, W. A. | |
dc.contributor.committeeMember | Williams, J. D. | |
dc.contributor.committeeMember | Sis, R. F. | |
dc.type.genre | dissertations | en |
dc.type.material | text | en |
dc.format.digitalOrigin | reformatted digital | en |
dc.publisher.digital | Texas A&M University. Libraries | |
dc.identifier.oclc | 15343062 |
Files in this item
This item appears in the following Collection(s)
-
Digitized Theses and Dissertations (1922–2004)
Texas A&M University Theses and Dissertations (1922–2004)
Request Open Access
This item and its contents are restricted. If this is your thesis or dissertation, you can make it open-access. This will allow all visitors to view the contents of the thesis.