Abstract
Five experiments were performed utilizing Japanese quail (Coturnix c. japonica) to determine the effects of the lipotropic agents, chlorine chloride and inositol, on the elimination of selected chlorinated hydrocarbons from the body. Supplementation of the diet with 2645 grams of chlorine chloride and 2000 grams of inositol per 1000 kilograms was effective in accelerating the rate of elimination of the chlorinated hydrocarbons, DDT and heptachlor. The addition of 10 percent vegetable oil to the basal diet increased the quantity of the chlorinated hydrocarbon residues retained in the tissue samples studied. An increase in liver weight was observed in the groups receiving the diets supplemented with chlorine chloride and inositol. This indicates increased hepatic activity due to a more rapid mobilization and metabolism of the chlorinated hydrocarbons studied. Supplementation of the basal diet with chlorine chloride or inositol singly at levels of 2645 grams or 2000 grams per 1000 kilograms, respectively, was effective in reducing the total quantity of body fat but was not effective in reducing the total carcass residue of DDT and metabolites. Under these experimental conditions, supplementation of the basal diet of mature laying Japanese quail with 1323 grams of chlorine chloride and 1000 grams of inositol per 1000 kilograms was as effective as supplementation with 2645 grams of chlorine chloride and 2000 grams of inositol per 1000 kilograms in accelerating the elimination of DDT and metabolites from the body..
Kubena, Leon Franklin (1971). The effects of certain dietary factors on the elimination of various chlorinated hydrocarbons. Doctoral dissertation, Texas A&M University. Texas A&M University. Libraries. Available electronically from
https : / /hdl .handle .net /1969 .1 /DISSERTATIONS -178563.