Mapping the Bend Loci on the Human Papillomavirus 16 Genome
Abstract
Physical mapping of the bend loci in HPV 16 may lead to an improved understanding of the transcriptional regulation of this genome. Subcloning small fragments of HPV 16 into pUC18 and pCY7, followed by electrophoretic analysis of the clones, provided a way of determining the location of bend loci. Of the 35.7% of the genome analyzed for bending, three bends were located. One was localized to a region containing an E2 open reading frame. The bend's center was graphically determined to lie between 2850 and 2910 bp.
Description
Program year: 1990/1991Digitized from print original stored in HDR
Citation
Hayes, Stacy Ann (1991). Mapping the Bend Loci on the Human Papillomavirus 16 Genome. University Undergraduate Fellow. Available electronically from https : / /hdl .handle .net /1969 .1 /CAPSTONE -WilliamsS _1991.