Purine Metabolism During Development in the Cellular Slime Mold, Dictyostelium discoideum
Abstract
The studies reported in this paper examine the metabolic reorientation of purine nucleotide metabolism during the development of the cellular slime mold, Dictyostelium discoideum. There appears to be an energy oriented redirection of purine nucleotide pools during development and these changes have been evaluated. The slime mold maintains its ability to synthesize nucleotides de novo and raises intracellular pools. Metabolic perturbations may be induced by a variety of purine and pyrimidine analogues and antimetabolites. All of these studies indicate that metabolic rearrangement of purine metabolism plays an integral role in the development of D. discoideum.
Description
Program year: 1978/1979Digitized from print original stored in HDR
Subject
slime moldDictyostelium discoideum
purine nucleotide pools
nucleotide synthesis
purine
pyrimidine analogues
Citation
Nail, Steven Gerald (1979). Purine Metabolism During Development in the Cellular Slime Mold, Dictyostelium discoideum. University Undergraduate Fellow. Available electronically from https : / /hdl .handle .net /1969 .1 /CAPSTONE -WilliamsR _1979.