Mapping The Bovine Cystic Fibrosis Gene

dc.contributor.advisor	Womack, James E.
dc.creator	Wallis, Deeann
dc.date.accessioned	2022-04-01T14:05:37Z
dc.date.available	2022-04-01T14:05:37Z
dc.date.issued	1993
dc.identifier.uri	https://hdl.handle.net/1969.1/CAPSTONE-WallisD_1993
dc.description	Program year: 1992/1993	en
dc.description	Digitized from print original stored in HDR	en
dc.description.abstract	Human cDNA probe H1. 6 (clone 10-1) encoding cystic fibrosis transmembrane conductance regulator (CFTR) was used to map the bovine homolog of CFTR. Using a panel of bovine X rodent hybrid somatic cells, the homolog was mapped to bovine syntenic group U13. CFTR is 97.7% concordant with syntenic markers T-cell receptor beta (TCRB) and P-glycoprotein 3 (PGY3) previously mapped on U13. The comparative gene maps of CFTR, TCRB, and PGY3 on human chromosome 7, bovine syntenic group U13, and mouse chromosomes 5 and 6 indicate considerable evolutionary conservation.	en
dc.format.extent	13 pages	en
dc.format.medium	electronic	en
dc.format.mimetype	application/pdf
dc.subject	cystic fibrosis	en
dc.subject	cystic fibrosis transmembrane conductance regulator	en
dc.subject	bovine	en
dc.subject	bovine syntenic group U13	en
dc.title	Mapping The Bovine Cystic Fibrosis Gene	en
dc.title.alternative	MAPPING THE BOVINE CYSTIC FIBROSIS GENE	en
dc.type	Thesis	en
thesis.degree.department	Veterinary Pathobiology	en
thesis.degree.grantor	University Undergraduate Fellow	en
thesis.degree.level	Undergraduate	en
dc.type.material	text	en