Comparative Studies on Nerve Growth Factor Isolated From the Mouse and Snake

dc.contributor.advisor	Moore, John B., Jr.
dc.creator	Appling, Dean R.
dc.date.accessioned	2022-04-01T15:59:51Z
dc.date.available	2022-04-01T15:59:51Z
dc.date.issued	1977
dc.identifier.uri	https://hdl.handle.net/1969.1/CAPSTONE-McLamoreR_1986
dc.description	Program year: 1976/1977	en
dc.description	Digitized from print original stored in HDR	en
dc.description.abstract	Nerve Growth Factor (NGF) was isolated and purified from the male mouse submaxillary gland and from lyophilized snake venom. Biological activity, isoelectric point and molecular weight were compared. Mouse NGF showed a maximum activity between 4 ng/ml and 35 ng/ml whereas snake NGF showed maximum activity in the 60 -550 ng/ml range. The beta-subunit of mouse NGF has a pI of 9.2 and the snake NGF showed a pI of 8.3 - 8.5. When snake NGF was subjected to SDS gel electrophoresis, the minimum molecular weight was determined to be approximately 10,000 daltons.	en
dc.format.extent	16 pages	en
dc.format.medium	electronic	en
dc.format.mimetype	application/pdf
dc.subject	Nerve Growth Factor	en
dc.subject	mouse	en
dc.subject	snake venom	en
dc.subject	Biological activity	en
dc.subject	isoelectric point	en
dc.subject	molecular weight	en
dc.title	Comparative Studies on Nerve Growth Factor Isolated From the Mouse and Snake	en
dc.type	Thesis	en
thesis.degree.department	Biochemistry	en
thesis.degree.grantor	University Undergraduate Fellow	en
thesis.degree.level	Undergraduate	en
dc.type.material	text	en