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G Protein-coupled Estrogen receptor is activated by G-1 which induces a signaling cascade that inhibits breast cancer cell proliferation
(2012-06-08)
Breast cancer is the most common cancer in women and is predominantly estrogen dependent [1]. About 1 in 8 women in the United States (12%) will develop invasive breast cancer over the course of her lifetime. Failure in ...
GENETIC ANALYSYS OF THE IN VIVO FUNCTION AND REGULATION OF THE ONCOPROTEIN CDK8 IN DROSOPHILA
(2012-05-09)
Cyclin-Dependent Kinase 8 (CDK8) has recently emerged as an oncoprotein that is amplified in both colorectal and melanoma cancers. The importance of CDK8 and its regulatory partner Cyclin C (CycC) is highlighted by the ...