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Characterization of the Brucella abortus rfb gene locus and the role of O-antigen in the resistance to complement lysis and macrophage defense mechanisms
(Texas A&M University, 1996)
In Gram-negative organisms, the lack of 0-antigen expression on the lipopolysaccharide molecule produces a rough phenotype which is associated with attenuation. Transposon mutagenesis of Brucella abortus with Tn5 generated ...