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Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases
(United States. Patent and Trademark Office, 2018-10-23)
The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases
(United States. Patent and Trademark Office, 2014-07-22)
The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof
(United States. Patent and Trademark Office, 2014-03-04)
The present invention provides aryl- or heteroaryl-diketo acid compounds effective to inhibit an activity of a Mycobacterial malate synthase enzyme or to inhibit a malate synthase activity in other bacteria having the ...
Variants of the lantibiotic MU1140 and other lantibiotics with improved pharmacological properties and structural features
(United States. Patent and Trademark Office, 2018-05-08)
The invention provides improvements of lantibiotics useful for reducing the numbers of microbes or the reproduction of microbes in or on subjects or objects. One embodiment of the invention provides variants of antibiotics ...