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Anticancer agents and use
(United States. Patent and Trademark Office, 2010-06-15)
Provided herein are compositions, all related stereoisomers as well as pharmaceutically acceptable salts provided as simplified analogs of pateamine A, in which the analogs generally are devoid of the C3-amino and C5-methyl ...
Beta-lactone compounds
(United States. Patent and Trademark Office, 2012-09-04)
The present invention provides compounds having the general structure A, or a pharmaceutically acceptable derivatives thereof:
wherein R is an alkyl group, and R1 comprises at least one moiety selected from a group ...
Potent, simplified derivatives of pateamine A
(United States. Patent and Trademark Office, 2007-06-12)
The present invention provides a compound of Formula I, all of its related stereoisomers, and their pharmaceutically acceptable salts, wherein A—B, K, Q, X, Y, Z, R and R1 are as defined in Claim 1. The present invention ...
Potent immunosuppressive agents, derivatives and uses
(United States. Patent and Trademark Office, 2014-09-23)
Provided herein include compositions, all related stereoisomers as well as pharmaceutically acceptable salts provided as simplified analogs of pateamine A, in which the analogs generally are devoid of the C3-amino and ...
Belactosin derivatives as therapeutic agents/biological probes and their synthesis
(United States. Patent and Trademark Office, 2012-02-21)
Derivatives of belactosin and their synthesis are disclosed. In certain embodiments, compounds of the present invention exhibit anti-cancer, antiviral, antibiotic, and/or auto-immune therapeutic abilities. In general, ...