Browsing Electronic Theses, Dissertations, and Records of Study (2002– ) by Subject "X-ray crystallography"
Now showing items 1-6 of 6
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(2022-02-02)Our understanding of gene essentiality in Mycobacterium tuberculosis (Mtb) has improved over the years. The introduction of these gene products into target-based drug discovery campaigns depends, in part, on whether or not ...
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(2012-10-19)Like all phages, T4 requires a holin (T) to effect lysis. The lysis event depends on the temporally regulated action of T, which accumulates in the inner membrane (IM) until, at an allele-specific time, it triggers to ...
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(2019-10-21)Lignin is the most abundant renewable aromatic in the world that has great potential as a sustainable source of monomeric units for the production of bioplastics. However, the chemical and biological processing of lignin ...
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(2013-05-16)The innate immune pathways that stimulate the expression of cytokines and proapoptotic factors in response to infection are triggered by the activation of the cytosolic receptors retinoic acid-inducible gene I (RIG-I) and ...
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(2012-08-20)Tridentate "pincer" ligands provide a unique balance of stability and reactivity in organometallic chemistry. The development of diarylamido-based PNP pincer ligands has led to many applications in catalysis, including the ...
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(2016-07-29)A key determinant of the pathogenicity of M. tuberculosis (Mtb) is its ability to conserve energy and resources by altering its intermediate metabolism response to host-derived hostile conditions. Growing evidence supports ...