Browsing Electronic Theses, Dissertations, and Records of Study (2002– ) by Author "Jain, Abhishek"
Now showing items 1-17 of 17
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Gold, Karli Ayn (2020-02-26)Vascular diseases, such as atherosclerosis and thrombosis, are the leading cause of morbidity and mortality worldwide. Despite major advancements to develop therapeutic interventions, the pathophysiology as it applies to ...
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A Microfluidic Model to Study Host-Microbiota Interactions in the Colorectal Tumor Microenvironemnt Penarete Acosta, Daniel Alfonso (2022-11-29)The colonic microbiota has been identified as a key player in the development of colorectal cancer. While changes in microbiota composition and function correlate with disease progression and treatment outcome, the mechanism ...
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Luna, David Jordan (2019-05-15)Bleeding and thrombosis episodes in children are often encountered during ECMO/VAD. Pediatric patients on ECMO are known to have compromised platelet function and depleted plasma factors, making them susceptible to bleeding ...
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Jia, Wenkai (2021-07-30)The importance of tissue-specific microenvironments in achieving physiological cell and tissue functions has spurred the advancement of extracellular matrix (ECM) scaffolds for tissue engineering. Unlike defined scaffolds ...
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Fuentes, Kevin (2020-07-16)In vivo animal models provide the most realistic information on flow dynamics and drug delivery research. However, the high cost of animal models, the inherent complexity of biological systems, and ethical concerns can ...
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Arun Kumar, Shreedevi (2021-07-15)Vaccines and chemotherapeutic agents have been developed to treat infectious diseases and cancer, respectively. However, efficacy of the therapeutic agents used to treat these diseases can be significantly improved through ...
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Leveraging Microfluidics and Electrokinetics to Improve Sample Preparation and Biomarker Detection Yost, Jarad Wilker (2023-03-30)With the advent of global pandemics, the world has developed a demonstrable need for rapid and low-cost testing platforms for diagnostics. Microfluidic diagnostics can meet this demand due to the versatility and scalability ...
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Rajeeva Pandian, Navaneeth Krishna (2021-08-25)Venous valves are anatomical structures in the veins, small and large, that help in the unidirectional flow of blood towards the heart. Unwanted clot (thrombus) formation at these valves and its subsequent complications ...
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Mathur, Tanmay (2022-12-12)Advances in tissue engineering and microfabrication techniques have skyrocketed the adoption of contemporary organ-chip biotechnology as an alternative disease and drug screening model compared to animals and traditional ...
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Bhat, Ankita Dattaprasad (2020-04-08)This project contributes to the development of a biocompatible, multi-analyte biotransducer and associated instrumentation that serves as a minimally invasive implantable biosensor system to improve patient stratification, ...
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Lawson, Zachary T (2021-12-01)Orthopedic biomechanics is the field of study wherein the principles of mechanics are applied to biological problems in the characterization, evaluation, and repair of the musculoskeletal system. Repair methods, such as ...
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Doria, Steven Michael (2023-01-23)Point of care (POC) instruments are a growing class of diagnostic tools designed for use in low resource settings, such as population screening, and rapid testing in traditional healthcare settings. The current state of ...
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Yost, Jarad Wilker (2020-04-08)Microfluidic PCR is one of the most common and widely used sample preparation techniques. Most heating methods for microfluidic PCR are heated in one of two ways: (1) the reaction is pumped between different boundary-heating ...
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Islam, Md Nazibul (2023-08-09)The recent outbreak of SARS-COVID-2 virus has emphasized the necessity for low-cost, portable, rapid, and sensitive biomolecule handling and detection systems for effective monitoring and management of pandemics and other ...
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Abasi, Sara (2020-04-10)A number of biochemical, mechanical, electrical and topographical factors serve as cues to orchestrate cellular responses. Tissue and regenerative engineering seek conditions wherein cells are exposed to cues similar in ...
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Jain, Abhishek (2014-08-05)In this thesis, we studied the problem of designing a down link scheduling policy to serve multiple types of clients from a base station in a time-varying wireless network. An ideal scheduling policy is fair among the ...
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Walther, Brandon Kurt (2023-01-09)Cells reside in complex physicochemical environments which provide forces acting as cues that influence the molecular physiology. However, the mechanisms and interactions between the various physical forces and the resultant ...