| dc.description.abstract | Healthcare professionals recommend many methods of restorative and therapeutic treatments, such as medicine, surgery, radiation, and rehabilitation to treat chronic diseases and conditions. However, evidence suggests that cultivating stem cells from permanent and deciduous teeth are an effective method to treat many oral and systemic conditions. There is a greater advantage to using stem cells from human exfoliated teeth (SHED) because of their differentiating capabilities, which allows for them to have diverse clinical applications. Deciduous teeth are often discarded after they are shed from the oral cavity, which reduces the likelihood of ethical considerations. In addition, stem cells obtained from teeth replicate at a quicker rate and for a longer period of time than other types of stem cells from the body. The process of isolating SHED is relatively uncomplicated and unlikely to generate pain. Additionally, since the transplant is obtained from the same individual, the individual does not demonstrate adverse immune reactions or rejections. The host and recipient are the same; therefore, the person is a 100% match to the stem cell. Hence, when compared to other types of adult stem cell harvesting, acquiring stem cells from deciduous teeth is noninvasive. SHED demonstrates great potential in treating patients with periodontal disease, namely reducing gingival bleeding, increasing new attachment of the periodontal ligament, and decreasing pocket depths. Oral healthcare providers should consider recommending SHED in their clinical practice due to their multi-differentiation potential, self-renewal capacity, and reported ease of the procedure. Further research is needed on the potential impact of regenerative therapies on patients with special healthcare needs.
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