Functionalized protein-based materials and their uses
Abstract
Embodiments of the invention are directed to Ubx-fusion molecules that maintain their mechanical strength and properties even after being fused with Ubx. Ubx fusions with VEGF and other growth factors, cell signaling proteins, and cell binding proteins can be used to induce angiogenesis. Ubx fibers and mesh, embedded within a tissue engineering scaffold, induce formation of vasculature within the scaffold. The presence of vasculature is necessary to provide oxygen and nutrients to other cells growing within the scaffold.
Subject
A61K 38/1825A61K 38/08
A61K 38/1866
A61K 9/7007
A61K 9/70
A61K 38/16
A61K 38/1767
C07K 14/43581
A61K 38/195
A61K 2300/00
Collections
Citation
Bondos, Sarah; Bayless, Kayla; Matthews, Kathleen; Patterson, Jan; Abbey, Colette; Howell, David; Hsiao, Hao-Ching; Churion, Kelly; Tsai, Shang-Pu; Ramasamy, Sandhya; Porterpan, Dustin; Northern, Keira (2021). Functionalized protein-based materials and their uses. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /193342.