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    Compositions and methods of enhancing immune responses to enteric pathogens

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    10376571.pdf (2.345Mb)
    Date
    2019-08-13
    Author
    Bielke, Lisa
    Layton, Sherryll
    Hargis, Billy
    Pumford, Neil R.
    Faulkner, Olivia B.
    Berghman, Luc
    Abi-Ghanem, Daad
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    Abstract
    Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD154 polypeptide or an HMGB1 polypeptide.
    URI
    https://hdl.handle.net/1969.1/177886
    Subject
    A61K 39/0275
    A61K 39/0258
    A61K 39/105
    A61K 39/107
    C07K 16/1232
    C12N 15/85
    A61K 2039/523
    A61K 2039/53
    C07K 2317/34
    Y02A 50/474
    Y02A 50/482
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    • Texas A&M University Patents
    Citation
    Bielke, Lisa; Layton, Sherryll; Hargis, Billy; Pumford, Neil R.; Faulkner, Olivia B.; Berghman, Luc; Abi-Ghanem, Daad (2019). Compositions and methods of enhancing immune responses to enteric pathogens. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /177886.

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