Compositions and methods of enhancing immune responses
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Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.
Bottje, Walter; Hargis, Billy; Berghman, Luc; Kwon, Young Min; Cole, Kimberly; Cox, Mandy; Layton, Sherryll (2018). Compositions and methods of enhancing immune responses. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from