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    Compositions and methods of enhancing immune responses

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    10004798.pdf (2.158Mb)
    Date
    2018-06-26
    Author
    Bottje, Walter
    Hargis, Billy
    Berghman, Luc
    Kwon, Young Min
    Cole, Kimberly
    Cox, Mandy
    Layton, Sherryll
    Metadata
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    Abstract
    Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.
    URI
    https://hdl.handle.net/1969.1/177256
    Subject
    C12N 15/102
    A61P 31/16
    A61K 39/145
    A61K 35/74
    A61K 39/0275
    A61P 37/04
    A61K 39/12
    Y02A 50/482
    C07H 21/04
    A61K 2039/552
    A61K 2039/55516
    Y02A 50/30
    A61K 2039/523
    C12N 2760/16134
    A61K 39/00
    A61K 2039/6006
    A61K 2035/11
    A61K 2039/522
    A61K 2039/6031
    Collections
    • Texas A&M University Patents
    Citation
    Bottje, Walter; Hargis, Billy; Berghman, Luc; Kwon, Young Min; Cole, Kimberly; Cox, Mandy; Layton, Sherryll (2018). Compositions and methods of enhancing immune responses. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /177256.

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