Replacement therapy for dental caries
Abstract
The invention provides recombinant Streptococcus mutans strains that can be used to improve oral health. An embodiment of the invention provides a method of reducing the incidence or severity of dental caries in a dental caries-susceptible host comprising administering orally to the host an isolated recombinant S. mutans strain of the invention in an amount effective for replacement of dental caries-causing S. mutans host strains in the oral cavity of the host. The isolated recombinant S. mutans strain 10 can be contained in a mouthwash, toothpaste, chewing gum, floss, chewable tablet, food, or beverage.
Subject
C07K 14/195A01N 25/34
A01N 63/02
A23G 4/123
A23L 1/3014
A23L 2/52
A61K 8/99
A61K 35/744
A61K 38/164
A61K 39/09
A61K 45/06
A61Q 11/00
C07K 14/315
C12N 9/0006
A23V 2002/00
A61K 38/12
A61K 39/02
A61K 2800/74
C12Y 101/01001
Collections
Citation
Hillman, Jeffrey D.; Smith, James Leif; Wilson-stanford, Shawanda R. (2016). Replacement therapy for dental caries. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /177135.