Texas A&M University LibrariesTexas A&M University LibrariesTexas A&M University Libraries
    • Help
    • Login
    OAKTrust
    View Item 
    •   OAKTrust Home
    • University Libraries
    • Business Library and Collaboration Commons
    • Texas A&M University Patents
    • View Item
    •   OAKTrust Home
    • University Libraries
    • Business Library and Collaboration Commons
    • Texas A&M University Patents
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Specific binding sites in collagen for integrins and use thereof

    Thumbnail
    View/ Open
    8252553.pdf (1.902Mb)
    Date
    2012-08-28
    Author
    Hook, Magnus
    Xu, Xuejun
    Kim, Jiyeun
    Metadata
    Show full item record
    Abstract
    The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising this novel sequence and the use of the peptides in enabling cell adhesion. Also provided herein are methods to identify specific integrin inhibitors, sequences of these inhibitors and their use in inhibiting pathophysiological conditions that may arise due to integrin-collagen interaction.
    URI
    https://hdl.handle.net/1969.1/177003
    Subject
    435/69.1
    435/320.1
    536/23.5
    C07K 7/06
    C07K 14/00
    G01N 33/566
    A61P 29/00
    G01N 33/6887
    C07K 14/78
    A61P 35/00
    A61P 35/04
    G01N 2333/78
    G01N 2500/02
    G01N 2333/70546
    Collections
    • Texas A&M University Patents
    Citation
    Hook, Magnus; Xu, Xuejun; Kim, Jiyeun (2012). Specific binding sites in collagen for integrins and use thereof. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /177003.

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Advanced Search

    Browse

    All of OAKTrustCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsDepartmentTypeThis CollectionBy Issue DateAuthorsTitlesSubjectsDepartmentType

    My Account

    LoginRegister

    Statistics

    View Usage Statistics
    Help and Documentation

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV