Show simple item record

dc.creatorHook, Magnus
dc.creatorPatti, Joseph M.
dc.creatorHouse-pompeo, Karen L.
dc.creatorSpeziale, Pietro
dc.creatorJoh, Danny
dc.creatorMcgavin, Martin J.
dc.date.accessioned2019-06-17T17:06:26Z
dc.date.available2019-06-17T17:06:26Z
dc.date.issued2012-07-03
dc.identifier.urihttp://hdl.handle.net/1969.1/176992
dc.description.abstractDisclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus aureus, the fnbA and fnbB genes of Streptococcus dysgalactiae, and the sfb gene of Streptococcus pyogenes, and nucleic acid segments encoding these peptides and epitopes. The anti-(fibronectin binding site) antibodies, peptides and epitopes that give rise to antibodies that block the binding of fibronectin binding proteins to fibronectin, and DNA segments encoding these proteins and are of use in various screening, diagnostic and therapeutic applications including active and passive immunization and methods for the prevention of streptococcal and staphylococcal colonization in animals or humans. These. DNA segments and the peptides derived therefrom are proposed to be of use directly in the preparation of vaccines and also for use as carrier proteins in vaccine formulations.en
dc.languageeng
dc.publisherUnited States. Patent and Trademark Office
dc.rightsPublic Domain (No copyright - United States)en
dc.rights.urihttp://rightsstatements.org/vocab/NoC-US/1.0/
dc.titleTreatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteinsen
dc.typeUtility patenten
dc.format.digitalOriginreformatted digitalen
dc.description.countryUS
dc.contributor.assigneeUniversity of Manitoba
dc.contributor.assigneeUniversita' Degli Studi di Pavia
dc.contributor.assigneeTexas A&M University System
dc.identifier.patentapplicationnumber11/589760
dc.subject.uspcprimary424/145.1
dc.subject.uspcother530/388.25
dc.date.filed2006-10-31
dc.publisher.digitalTexas A&M University. Libraries


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record