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dc.creatorHook, Magnus
dc.creatorLukomski, Slawomir
dc.creatorXu, Yi
dc.date.accessioned2019-06-17T17:04:44Z
dc.date.available2019-06-17T17:04:44Z
dc.date.issued2010-04-20
dc.identifier.urihttp://hdl.handle.net/1969.1/176921
dc.description.abstractThe present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of repeated Gly-Xaa-Yaa triplets and, optionally, one or more domains from a mammalian collagen. Also provided are expression vectors and host cells containing the expression vectors to produce these recombinant proteins and methods of producing the same. Additionally, antibodies are provided that are directed against a recombinant collagen-like protein that, preferably, binds an integrin. Furthermore, a method of screening for potential therapeutic compounds that inhibit the integrin-binding or integrin-interacting activities of recombinant collagen-like proteins.en
dc.languageeng
dc.publisherUnited States. Patent and Trademark Office
dc.rightsPublic Domain (No copyright - United States)en
dc.rights.urihttp://rightsstatements.org/vocab/NoC-US/1.0/
dc.titleProkaryotic collagen-like proteins and uses thereofen
dc.typeUtility patenten
dc.format.digitalOriginreformatted digitalen
dc.description.countryUS
dc.contributor.assigneeThe Texas A&M University System
dc.identifier.patentapplicationnumber12/455840
dc.subject.uspcprimary530/356
dc.subject.uspcother530/350
dc.date.filed2009-06-08
dc.publisher.digitalTexas A&M University. Libraries


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