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    Proteins and polypeptides from coagulaslase-negative staphylococci

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    Date
    2009-01-06
    Author
    Foster, Timothy J.
    Mccrea, Kirk
    Hook, Magnus A. O.
    Davis, Stacy
    Nieidhin, Deirdre
    Hartford, Orla
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    Abstract
    Proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, SdrG and SdrH, and their effective fragments such as their respective A domains, are provided which are useful in the prevention and treatment of infection caused by coagulase-negative staphylococcal bacteria such as S. epidermidis. The SdrF, SdrG and SdrH proteins are cell-wall associated proteins that specifically bind host proteins and which each have a highly conserved motif of which the consensus sequence is TYTFTDYVD (SEQ ID NO: 16). The proteins and polypetides may be useful in generating antibodies for the diagnosis and treatment of coagulase-negative staphylococcal infections.
    URI
    https://hdl.handle.net/1969.1/176890
    Subject
    530/350
    435/69.1
    536/23.7
    C07K 14/31
    A61P 31/04
    G01N 33/56938
    A61P 9/00
    C07K 16/1271
    A61P 19/00
    A61P 17/02
    A61K 39/00
    A61K 2039/505
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    • Texas A&M University Patents
    Citation
    Foster, Timothy J.; Mccrea, Kirk; Hook, Magnus A. O.; Davis, Stacy; Nieidhin, Deirdre; Hartford, Orla (2009). Proteins and polypeptides from coagulaslase-negative staphylococci. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /176890.

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