Pyridinium cationic lipids as gene transfer agents
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Pyridinium cationic lipids useful as non-viral gene delivery agents are disclosed. The agents are prepared by reaction of pyrylium salts with primary amines. Also disclosed are methods of trasfectind cells using the pyridinium cationic lipids as gene transfer agents.
Balaban, Alexandru T.; Seitz, William A.; Ilies, Marc A. C.; Thompson, Edward Bradbridge; Garfield, Robert E.; Johnson, Betty H.; Miller, Aaron L.; Wentz, Melissa J. (2008). Pyridinium cationic lipids as gene transfer agents. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from