Recombinant virus expressing foreign DNA encoding feline CD86 and uses thereof
Abstract
The present invention involves a recombinant virus which comprises at least one foreign nucleic acid inserted within a non-essential region of the viral genome of a virus, wherein each such foreign nucleic acid encodes a protein. The protein which is encoded is selected from the groups consisting of a feline CD28 protein or an immunogenic portion thereof, a feline cD80 protein or an immunogenic portion thereof, a feline CD86 protein or an immunogenic portion thereof, or a feline CTLA-4 protein or an immunogenic portion thereof. The protein is capable of being expressed when the recombinant virus is introduced into an appropiate host. The present invention also involves a recombinant virus further comprising a foreign nucleic acid encoding an immunogen derived from a pathogen. The present invention also comprises recombinant viruses which are capable of enhancing an immune response in a feline. The present invention also comprises recombinant viruses which are capable of suppressing an immune respons in a feline.
Subject
536/23.72424/199.1
424/204.1
424/207.1
424/224.1
424/229.1
424/234.1
536/24.1
A61K 39/275
A61K 38/1774
A61P 35/00
A61K 39/39
A61K 39/00
A61K 38/208
A61P 43/00
A61K 2300/00
A61K 2039/55516
A61K 2039/5256
Collections
Citation
Winslow, Barbara J.; Cochran, Mark D.; Hash, Stephen; Choi, Insoo; Collisson, Ellen (2007). Recombinant virus expressing foreign DNA encoding feline CD86 and uses thereof. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /176859.