Peptide inhibitor of fibrinogen blood clotting
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A method of inhibiting fibrin clot formation is provided. The decorin protein, peptide, or related fragments are found to bind fibrinogen in the presence of Zinc (Zn2+), thus preventing the formation of fibrin clots. The decorin protein, peptide, or related fragments can be utilized as an anticoagulant and in methods of preventing and/or treating diseases and disorders characterized by clot formation.
Hook, Magnus A.; Yang, Vivian W-C (2002). Peptide inhibitor of fibrinogen blood clotting. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from