Peptide inhibitor of fibrinogen blood clotting
Abstract
A method of inhibiting fibrin clot formation is provided. The decorin protein, peptide, or related fragments are found to bind fibrinogen in the presence of Zinc (Zn2+), thus preventing the formation of fibrin clots. The decorin protein, peptide, or related fragments can be utilized as an anticoagulant and in methods of preventing and/or treating diseases and disorders characterized by clot formation.
Subject
514/13.6435/7.1
435/217
435/810
514/13.7
514/822
A61K 38/1709
C07K 14/4725
C07K 14/47
A61P 7/02
Y10S 435/81
Y10S 514/822
Collections
Citation
Hook, Magnus A.; Yang, Vivian W-C (2002). Peptide inhibitor of fibrinogen blood clotting. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /176695.