Emulsions of perfluoro compounds as solvents for nitric oxide (NO)
Abstract
The present invention involves perfluoro compound emulsions including nitric oxide, their preparation and their use. These emulsions provide a new source of nitric oxide. Such nitric oxide-containing emulsions may be used for the administration of nitric oxide to individuals in need thereof. Individuals in need of nitric oxide administration can include those suffering from hypertension, preeclampsia and a number of other situations where an increased blood flow, for example, is desirable. In addition, given the long use of perfluoro compound emulsions as blood substitutes, the present invention provides a relatively safe mode for administering and distributing nitric oxide-without potential negative side effects such as toxicities due to drug metabolites.
Subject
514/746424/673
424/718
514/743
514/759
514/832
514/833
A61P 9/04
A61K 33/00
A61P 9/00
A61P 9/12
A61K 9/0026
Y10S 514/833
Y10S 514/832
Collections
Citation
Garfield, R. E.; Balaban, A. T.; Seitz, W. A. (1999). Emulsions of perfluoro compounds as solvents for nitric oxide (NO). United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /176606.