Assessing the effect of obesity by optical spectroscopy
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It is hypothesized that an increase in adipose tissue rigidity can both limit swelling and shrinking of adipocytes which predisposes people to obesity related health problems. Taking into account the alarming trend of increased obesity rates in the nation, it is important to examine the effect of diet on the body. Raman spectroscopy allows non-invasive chemical assessment, while Brillouin spectroscopy affords non-invasive measurements of local elasticity of tissues, which, as we hypothesize, are being affected by obesity. In this study, a group of rats were fed a diet supplemented with high-lipids while the control group was fed a regular diet. Two spectroscopic techniques were used to evaluate the variations of chemical and mechanical properties in the skin, inguinal and interscapular adipose tissues between the two groups. Supplementary measurements were collected from the femoral vein and artery.
Gobbell, Cassidy Nicole (2017). Assessing the effect of obesity by optical spectroscopy. Undergraduate Research Scholars Program. Available electronically from