| dc.description.abstract | Total Knee Arthroplasty (TKA) is a common treatment for patients with severe knee pain due to osteoarthritis, a condition characterized by the loss of articular cartilage or injury. Most patients that opt to proceed with a TKA procedure report effective pain mitigation; however, approximately 30% do not realize sufficient pain relief following the procedure. This post-operative pain is typically associated with fixation, integration, and mechanical complications that can lead to a loss of bone mass. In cases where the procedure is successful, a revision procedure may still be required as the lifespan of the device is limited to 10-20 years when problems with fixation culminate in total failure of the device. The proposed research will evaluate a TKA device that incorporates unique geometrical and mechanical properties that address the problems associated with initial and long-term fixation, as well as component wear. Consequently, this technology is expected to enhance the quality of life of the patient, as well as potentially eliminate the need for revision procedures. | en |
