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Contour Collimation Systems to be Used for Murine Irradiation
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Three collimators were designed and built with mouse irradiation in mind. They were made to have a shapeable aperture that could deliver strange or complex dose shapes to spots on the animals. Current collimators are either custom-built, expensive, or only provide limited dose shapes. These provide self-customizable collimation at a minimum of cost. A mouse holder was also devised to reproducibly hold a mouse under the collimator. Construction of the holder and of each collimator is also covered. Each collimator was analyzed for flaws, holes, and penumbral width across various shapes of interest. A Norelco MG300 X-ray generator at the Texas A&M Nuclear Science Center was used in these tests. The lead collimator had a radial penumbra of 1.2 mm. The clay / lead shot collimator had a radial penumbra of 1.6 mm. The brass collimator had a radial penumbra of 1.75 mm. Vertical and horizontal penumbras are dependent on distance from the center of the beam. All readings are + 0.3 mm according to the resolution of the scanner used in this experiment. Each collimator is useful for different purposes.
Uhlemeyer, James Richard (2013). Contour Collimation Systems to be Used for Murine Irradiation. Master's thesis, Texas A&M University. Available electronically from