Ultrasound-modulated optical tomography for biomedical applications
dc.contributor.advisor | Wang, Lihong V. | |
dc.creator | Li, Jun | |
dc.date.accessioned | 2004-11-15T19:53:10Z | |
dc.date.available | 2004-11-15T19:53:10Z | |
dc.date.created | 2004-08 | |
dc.date.issued | 2004-11-15 | |
dc.identifier.uri | https://hdl.handle.net/1969.1/1274 | |
dc.description.abstract | I experimentally studied ultrasound-modulated optical tomography, which holds the promise for biomedical diagnosis. I measured the degree of polarization of laser speckles generated by scattered light transmitted through turbid media, investigated three signal-detection schemes for extracting the intensity of the ultrasound-modulated light, carried out experiments to image thick biological-tissue samples, and studied two techniques providing resolution in the cross-sections containing the ultrasonic axis. The study of degree of polarization presented results important for the understanding of polarization phenomena in turbid media. I explored an optical-filtering based signal detection scheme, improved the parallel-lock-in speckle detection scheme and proposed a speckle-contrast detection scheme. With the speckle-contrast detection scheme, I successfully obtained images of biological-tissue samples up to 50 mm thick. Further I studied frequency-swept ultrasound-modulated optical tomography for sub-millimeter resolution imaging, and developed ultrasound-modulated optical computed tomography that was based on a back-projection image reconstruction method and obtained clear images of biological-tissue samples. | en |
dc.format.extent | 907678 bytes | en |
dc.format.extent | 158110 bytes | en |
dc.format.medium | electronic | en |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Texas A&M University | |
dc.subject | ultrasound | en |
dc.subject | optical | en |
dc.subject | tomography | en |
dc.subject | modulation | en |
dc.subject | biomedical | en |
dc.title | Ultrasound-modulated optical tomography for biomedical applications | en |
dc.type | Book | en |
dc.type | Thesis | en |
thesis.degree.department | Biomedical Engineering | en |
thesis.degree.discipline | Biomedical Engineering | en |
thesis.degree.grantor | Texas A&M University | en |
thesis.degree.name | Doctor of Philosophy | en |
thesis.degree.level | Doctoral | en |
dc.contributor.committeeMember | Coté, Gerard L. | |
dc.contributor.committeeMember | Humphrey, Jay D. | |
dc.contributor.committeeMember | Eknoyan, Ohannes | |
dc.type.genre | Electronic Dissertation | en |
dc.type.material | text | en |
dc.format.digitalOrigin | born digital | en |
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