Browsing by Subject "telomerase"
Now showing items 1-4 of 4
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(2013-07-26)Telomeres are the ends of linear chromosomes tasked with preventing their recognition by the DNA damage machinery and providing a mechanism to solve the end replication problem. The telomeric DNA is mostly double-stranded, ...
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(2021-03-25)Telomerase is a specialized ribonucleoprotein (RNP) complex responsible for telomere maintenance. Telomerase consists of three essential components: the catalytic subunit telomerase reverse transcriptase TERT, the telomerase ...
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(Texas A&M University, 2006-04-12)Telomerase is the key enzyme synthesizing telomeric DNA in most eukaryotic organisms. In mammals, telomerase expression is abundant in the germline cells but is undetectable in most other differentiated organs. Intensive ...
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(2011-08-08)Telomeres are the physical ends of linear chromosomes in eukaryotes. Telomeres not only protect chromosome ends from being recognized as double-strand breaks but also maintain the chromosome terminal sequences. These ...