Browsing by Subject "phosphofructokinase"
Now showing items 1-7 of 7
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(2015-05-08)To better understand the relationship between allosteric ligand structure and the resulting allosteric behavior, we investigated the roles that functional groups and structure play in the binding affinity and allosteric ...
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Exploration of the Interplay Between Allosteric Interactions of Phosphofructokinase From Rat Liver (2018-01-17)The key metabolic enzyme phosphofructokinase (PFK) catalyzes the phosphorylation of fructose-6-phosphate (Fru-6-P) by MgATP in the first committed step of glycolysis. PFK’s phosphorylation activity is tightly regulated by ...
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(2015-12-12)Phosphofructokinase from Bacillus stearothermophilus (BsPFK) and Escherichia coli (EcPFK) are allosterically inhibited by downstream glycolytic pathway intermediate phosphoenol-pyruvate (PEP). The coupling free energy, ...
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(2016-04-08)Phosphofructokinase (PFK) catalyzes the phosphorylation of fructose 6-phosphate (F6P) to fructose 1,6-bisphosphate (F16BP) in a MgATP dependent reaction. This reaction represents the first committed step of the glycolytic ...
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(2012-10-17)The number of allosteric sites and active sites in phosphofructokinase from Bacillus stearothermophilus create an intricate network of communication within the enzyme. With thermodynamic linkage analysis, the overall ...
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(Texas A&M University, 2005-02-17)Phosphofructokinase from Escherichia coli (EcPFK) is allosterically regulated by MgADP and phospho(enol)pyruvate (PEP). Both molecules compete for binding to the same allosteric site, however, MgADP activates and PEP ...
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(Texas A&M University, 2004-09-30)Phosphofructokinase from Bacillus stearothermophilus (BsPFK) is a homotetrameric enzyme with an average of one active site and one allosteric site per subunit. BsPFK is inhibited by phosphoenolpyruvate (PEP) and how this ...