Browsing by Subject "mitochondria"
Now showing items 1-20 of 22
-
(2019-08-14)Lions are a flagship species, meaning that as a large, charismatic carnivore, research and conservation for the lion influences many other species that share its habitat. Proper management requires understanding of a ...
-
(Texas A&M University, 2006-08-16)Most proteins residing in the mitochondrial matrix are synthesized in the cytosol and post-translationally imported into the mitochondrial matrix. The matrix-targeted preproteins traverse the outer mitochondrial membrane ...
-
(2013-08-30)The speciation of iron in intact Jurkat cells and their isolated mitochondria was assessed using biophysical methods. [Fe4S4]^(2+) clusters, low-spin (LS) Fe^(II) heme centers, non-heme high-spin (NHHS) FeII species, ...
-
(2020-04-16)Copper is required for the assembly and activity of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain. As a multi-subunit metalloprotein, CcO biogenesis involves many assembly factors ...
-
(2019-07-15)Mitochondrial health is pertinent to optimizing athletic performance and is maintained in part by dietary antioxidants such as selenium (Se) and vitamin E (vitE). Mitochondrial adaptations to elevated dietary Se coupled ...
-
(2009-05-15)Traditional methods of oocyte selection for in vitro studies have proven inefficient with respect to achieving a level of predictability for competency. In this study, a novel method of oocyte selection was implemented ...
-
(2019-07-08)Commercial meat-chickens (broilers) have been heavily selected for performance traits including high body weights, large breast muscle size, and improved feed efficiency. The wooden breast condition (WB) is a consequence ...
-
(2015-08-05)The mitochondrial respiratory chain (MRC) consists of four multi-protein complexes in the inner membrane of mitochondria and is the main site of cellular respiration. MRC biogenesis is facilitated by several assembly ...
-
Influence of Insulin Resistance on Contractile Activity-Induced Anabolic Response of Skeletal Muscle (2011-02-22)Although the long-term therapeutic benefits of exercise are indisputable, contractile activity may induce divergent adaptations in insulin-resistant vs. insulin-sensitive skeletal muscle. The purpose of this study was to ...
-
(2010-07-14)The longstanding view has been that metabolism allows for cell division to take place, but that metabolic processes do not actively promote cell division. I have recently challenged this notion by identifying a unique ...
-
(2019-07-24)Copper is required for the activity of cytochrome c oxidase (CcO), the mitochondrial enzyme that catalyzes cellular respiration. Copper delivery to CcO is a complex process requiring a number of proteins, and loss-of-function ...
-
(2011-02-22)T helper (Th) cell activation is necessary for the adaptive immune response. Formation of an immunological synapse (IS) between Th cells and antigen-presenting cells is the first step in Th cell activation. In vitro studies ...
-
(2021-01-13)The control of cell metabolism is intimately linked to the size and shape of mitochondria, which varies significantly across cell types. Mitochondria can elongate (fuse) with other nearby mitochondria, or they can fragment ...
-
(2022-12-09)Photobiomodulation is a therapeutic technique that has been shown to aid in bone regeneration, traumatic brain injury, and wound care, among others. The main hallmark of photobiomodulation is that it uses a low-energy light ...
-
(2021-10-28)Biochemical interactions between macromolecules form the basis of life. Among different macromolecular interactions present in living systems, we still lag in our understanding of how lipids influence the structure and ...
-
The goal of this project is to determine how physiological levels of polyphosphate affect cellular metabolism in the model organism Dictyostelium discoideum. Understanding the effects of polyphosphate on a molecular level ...
-
(2012-07-16)The overall goal of this research was to investigate oxidative stress related changes to the proteomes of 3T3-L1 adipocytes and an inducible CYP2E1 expressing HepG2 cells. Enhanced oxidative stress in hypertrophic adipocytes ...
-
(2010-10-12)The pantherine lineage of cats diverged from the remainder of modern Felidae less than 11 million years ago. This clade consists of the five big cats of the genus Panthera, the lion, tiger, jaguar, leopard, and snow leopard, ...
-
(2018-05-09)Small GTPase Rnd3 participates in a broad spectrum of pathological processes. The downregulation of Rnd3 is observed in heart failure patients, and causes cardiac dysfunction in animal models. The dysfunction of mitochondria ...
-
(Texas A&M University, 2006-10-30)Electron paramagnetic resonance (EPR) and Mössbauer spectroscopy were used to examine the distribution of iron in mitochondria from Saccharomyces cerevisiae. These organelles were packed into EPR and Mössbauer cuvettes, ...