Browsing by Subject "isocitrate lyase"
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(2019-01-14)Isocitrate lyase 1 & 2 are essential enzymes for Mycobacterium tuberculosis pathogenicity and antibiotic resistance, and thereby, are appealing targets for the treatment of latent tuberculosis. Since high-throughput screening ...
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(2019-02-12)This dissertation covers projects focused on the drug design and characterization of novel bacterial drug targets. The first project centers on acetolactate synthase (ALS), a key enzyme involved in the biosynthesis of ...