Browsing by Subject "enzyme kinetics"
Now showing items 1-4 of 4
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(2019-01-14)Isocitrate lyase 1 & 2 are essential enzymes for Mycobacterium tuberculosis pathogenicity and antibiotic resistance, and thereby, are appealing targets for the treatment of latent tuberculosis. Since high-throughput screening ...
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(2021-04-15)Human diseases caused by the genus Trypanosoma, including Chagas disease and African sleeping sickness, affect millions of people and cause enormous socioeconomic burdens in impoverished areas. However, neither vaccines ...
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(2011-10-21)Bacillus stearothermophilus phosphofructokinase (BsPFK) is a homotetramer that is allosterically inhibited by phosphoenolpyruvate (PEP), which binds along one dimer-dimer interface. The substrate, fructose-6-phosphate ...
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(2012-12-10)Understanding how protein sequence, structure and function coevolve is at the core of functional genome annotation and protein engineering. The fundamental problem is to determine whether sequence variation contributes to ...