Browsing by Subject "cryo-EM"
Now showing items 1-3 of 3
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(2021-07-26)Single-stranded RNA bacteriophages (ssRNA phages) infect Gram-negative bacteria via a single maturation protein (Mat), which attaches to a retractile pilus of the host. In this thesis work, I explored interactions between ...
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(2021-04-12)Nearly half of clinically used antibiotics target ribosome, the vital translational machinery for bacterial survival. In this dissertation, we studied the translational regulation and antibiotic resistance in Mycobacterium ...
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(2021-12-07)Ribosomes translate RNA into proteins. The protein synthesis inhibitor cycloheximide (CHX) is widely used to inhibit eukaryotic ribosomes engaged in translation elongation. However, the lack of structural data for actively ...