Browsing by Subject "allosteric regulation"
Now showing items 1-5 of 5
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Exploration of the Interplay Between Allosteric Interactions of Phosphofructokinase From Rat Liver (2018-01-17)The key metabolic enzyme phosphofructokinase (PFK) catalyzes the phosphorylation of fructose-6-phosphate (Fru-6-P) by MgATP in the first committed step of glycolysis. PFK’s phosphorylation activity is tightly regulated by ...
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(2013-05-23)In 1996, scientists discovered a connection between the gene for the human protein frataxin (FXN) and the neurodegenerative disease Friedreich’s ataxia (FRDA). Decreased FXN levels result in a variety of aberrant phenotypes ...
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(Texas A&M University, 2005-02-17)Protein-ligand and protein-protein interactions are critical to cellular function. Most cellular metabolic and signal tranduction pathways are influenced by these interactions, consequently molecular level understanding ...
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(Texas A&M University, 2005-02-17)Phosphofructokinase from Escherichia coli (EcPFK) is allosterically regulated by MgADP and phospho(enol)pyruvate (PEP). Both molecules compete for binding to the same allosteric site, however, MgADP activates and PEP ...
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(2011-02-22)M. tuberculosis copper-sensitive operon repressor (Mtb CsoR) is the founding member of a new metalloregulatory protein family in prokaryotes that regulates the transcription of the cso operon in response to copper toxicity. ...