Browsing by Subject "X-ray crystallography"
Now showing items 1-3 of 3
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Deciphering Lysis and its Regulation in Bacteriophage T4
(2012-10-19)Like all phages, T4 requires a holin (T) to effect lysis. The lysis event depends on the temporally regulated action of T, which accumulates in the inner membrane (IM) until, at an allele-specific time, it triggers to ... -
Mechanism of MDA5 Recognition of Short RNA Ligands and Crystal Structure of PepQ
(2013-05-16)The innate immune pathways that stimulate the expression of cytokines and proapoptotic factors in response to infection are triggered by the activation of the cytosolic receptors retinoic acid-inducible gene I (RIG-I) and ... -
Organometallic Chemistry Supported by the PNP Pincer Framework for Both Early and Late Transition Metals
(2012-08-20)Tridentate "pincer" ligands provide a unique balance of stability and reactivity in organometallic chemistry. The development of diarylamido-based PNP pincer ligands has led to many applications in catalysis, including the ...