Browsing by Subject "Wnt"
Now showing items 1-7 of 7
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(2022-12-09)During early inner ear development, patterning of the sensory and neural domains is established in response to multiple signaling inputs. Although the importance of Fgf, Wnt, and Hh for inner ear development have been ...
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(2020-04-20)Beta-catenin (CTNNB1) is a key downstream effector of the WNT signaling pathway, a pathway involved in embryonic development and tumorigenesis. To further study the role of CTNNB1 in gut tumorigenesis, mice homozygous for ...
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(2013-02-04)Early in vertebrate development, the neural plate, from which the central nervous system forms, is subdivided into four gross domains through a process called patterning. Defects in neural plate patterning can have severe ...
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(Texas A&M University, 2006-04-12)Vertebrates have evolved a unique way to sense their environment: placodallyderived sense organs. These sensory structures emerge from a crescent-shaped domain, the preplacodal domain, which surrounds the anterior neural ...
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(2017-12-11)Wnt signaling has a conserved role in anterior-posterior (A-P) patterning of the remarkably complex vertebrate brain from a very basic primordium, the neural plate, by differentially regulating downstream target genes to ...
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(2016-11-23)In response to altered physiological demands, cardiac muscles remodel their muscle mass and contractile properties to sustain muscle performance. However, dramatic alterations of the sarcomere structure are rarely observed ...
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(2022-12-13)Bone- and tooth-related disorders are a major health burden in modern society. Identifying the cellular and molecular mechanisms of such disorders hold great potential in the development of novel therapeutic strategies. ...