Browsing by Subject "Per1"
Now showing items 1-2 of 2
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The Effect of Disrupted Circadian Rhythm and Associated microRNA on Biliary Injury and Malignant Transformation
(2014-12-12)Cholangiocarcinoma (CCA) is a devastating tumor characterized by late presentation of symptoms with limited treatment options. Disruption of circadian rhythm is associated with cancer development and progression. MicroRNAs ... -
Timing Matters: The Role of Circadian Clock Genes In Development and Toxin Responses
(2009-05-15)Most members of the PAS (PER-ARNT-SIM) protein family are transcription factors, mediating development and adaptive responses to the environment, such as circadian rhythms and toxin responses. Because the PAS domain mediates ...