Browsing by Subject "PXR"
Now showing items 1-4 of 4
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(2011-10-21)To understand the mechanisms of transcriptional regulation of PXR, we performed yeast two-hybrid screenings to search for PXR-interacting proteins in a human liver cDNA library using the PXR ligand binding domain as the ...
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(2010-01-16)Polycyclic aromatic hydrocarbons (PAHs) are widely distributed in the environment and are generated by many sources. Though the potential of PAH-rich mixtures to cause health effects has been known for almost a century, ...
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(2011-08-08)Pregnane X receptor (PXR) is a ligand-dependent transcription factor that plays an important role in xenobiotic/drug metabolism. The ligand-receptor interaction transcriptionally activates phase I and phase II enzymes, and ...
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(2016-05-24)Pregnane X receptor (PXR) is a ligand-activated nuclear receptor that regulates gene expression of the metabolizing enzymes that are involved in detoxification of endogenous and exogenous compounds in the gastrointestinal ...