Browsing by Subject "Mixture Model"
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Expectation-Maximization Based Mixture-Model Exploiting Pathway Knowledge for Cancer Heterogeneity (2017-05-08)Cancer cells are much more prone to mutations than normal cells, generating over time, more genetic variants of themselves within the tissue. Drugs designed for one variant might not work as intended for other variants. ...
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(2019-03-06)This dissertation includes three essays. In the first essay I study the problem of density estimation using normal mixture models. Instead of selecting the ‘right’ number of components in a normal mixture model, I propose ...