Browsing by Subject "Mass Spectrometry"
Now showing items 1-16 of 16
-
(2010-01-14)Imaging mass spectrometry (MS) analysis allows scientists the ability to obtain spatial and chemical information of analytes on a wide variety of surfaces. The ability to image biological analytes is an important tool in ...
-
(2014-05-05)The use of nanomaterials for sensing and biological applications has recently gained interest owing to the unique physical, chemical and optical properties that arise when materials are reduced to the nanoscale. The unique ...
-
(2020-06-24)Lipids are a group of biomolecules which play crucial roles in many biological functions such as cell membrane construction, energy storage, and signal transduction. The aberrant metabolism of lipids is involved in the ...
-
(Texas A&M University, 2005-08-29)Separations coupled to mass spectrometry (MS) are widely used for large-scale protein identification in order to reduce the adverse effects of analyte ion suppression, increase the dynamic range, and as a deconvolution ...
-
Development of Modular High-Resolution Ion Mobility Orbitrap Platforms for Native Mass Spectrometry (2021-10-28)Native ion mobility-mass spectrometry (IM-MS) has evolved into a multifunctional tool for the characterization and analysis of native intact protein complexes. Structural information can be inferred by the rotationally-averaged ...
-
(2013-05-08)The three dimensional structure of a protein is important for its function. When misfolded, a protein may be rendered inactive or adapt a conformation that could be toxic. Studying protein folding requires an understanding ...
-
(2017-08-02)Native electrospray ionization ion mobility mass spectrometry (ESI-IM-MS) allows for the investigation of complex heterogeneous mixtures of intact biomolecules according to their mass, charge, and size, which can provide ...
-
A distinct feature of secondary ion mass spectrometry, SMIS, with large projectiles, e.g. C60, Au400, Ar2000, is abundant secondary ion, SI, emission. Thus it is feasible to run experiments in the event-by-event bombardment ...
-
(2018-03-29)Atmospheric aerosols profoundly impact human health, visibility, the ecosystem, and the climate. Some aerosols are directly emitted, but a majority are formed in the atmosphere by the oxidation of gaseous precursors. ...
-
(2012-10-19)With the severity of cardiovascular disease (CVD) and the related mortality rate to this disease, new methods are necessary for risk assessment and treatment prior to the onset of the disease. The current paradigm in CVD ...
-
(2012-02-14)Drift tube ion mobility spectrometry (IMS) is a powerful, post-ionization separation that yields structural information of ions through an ion-neutral collision cross section. The ion-neutral collision cross section is ...
-
(2012-02-14)Mass spectrometry (MS) has played a major role in the proteomic analysis of an array of biological samples. Even so, inherent limitations exist such as sample complexity and the dynamic range. In an attempt to overcome ...
-
(2015-11-10)This dissertation is aimed at understanding the molecular composition and physical chemistry of secondary organic aerosols (SOA) and, in particular, the processes that lead to their formation and growth. Several analytical ...
-
(2016-08-04)Electrospray ionization ion mobility mass spectrometry (ESI-IM-MS) has emerged in recent years as a tool to separate heterogeneous conformer populations and determine ion-neutral collision cross sections (CCS). However, ...
-
Size-selected 2, 5, and 10 nm gold nanoparticles for laser desorption/ionization mass spectrometry (2009-05-15)The analytical utility of gold nanoparticles (AuNPs) for laser desorption/ionization mass spectrometry (LDI-MS) is examined here. An evaluation of the parameters that affect desorption/ionization show that careful treatments ...
-
(2012-11-06)High resolution mapping of molecular species, specifically sub-micrometer spatial resolution mapping, is at the forefront of recent interest in Secondary Ion Mass Spectrometry (SIMS). Large projectiles, e.g. C60, Au400, ...