Browsing by Subject "Major toxicology"
Now showing items 1-20 of 26
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(Texas A&M University. Libraries, 1993)2,3,7,8 -Tetrachlorodibenzo-p-dioxin (TCDD) is a broad spectrum antiestrogen which works through the aryl hydrocarbon (Ah) receptor. The estrogen receptor (ER) positive hum an ovarian carcinoma cell lines PE01, PE04 and ...
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(Texas A&M University. Libraries, 1992)Polychlorinated dibenzo-p-dioxins and dibenzofurans are environmental contaminants which elicit a number of toxic and biochemical effects including immunotoxicity, hepatic microsomal monooxygenase induction and enodcrine ...
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(Texas A&M University. Libraries, 1994)The present studies were conducted to assess cell-specific cytotoxic responses of the kidney to selected aromatic hydrocarbons (AHs) using in vitro culture systems of glomerular mesangial (GMCs) and cortical tubular ...
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(Texas A&M University. Libraries, 1990)The metabolism and/or toxicological effects of 3 mycotoxins were studied in poultry. In the metabolism study, a tritiated preparation of the trichothecene mycotoxin T-2 toxin was administered as a single oral dose to 21-day ...
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(Texas A&M University. Libraries, 1986)Lethal methyl parathion (MP) intoxication and recovery from nonlethal MP intoxication was investigated in 3 feral rodent species as well as their laboratory animal counterparts. The study animals were laboratory Sprague-Dawley ...
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(Texas A&M University. Libraries, 1986)The cis and trans isomers of the synthetic pyrethroid, resmethrin (5-benzyl-3-furylmethyl-(IRS)-chrysanthemate), labeled with radiocarbon in either the alcohol or acid moiety, were individually administered orally to White ...
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(Texas A&M University. Libraries, 1988)The competitive receptor binding affinities of thirteen 2- substituted-3,7,8-trichlorodibenzo-p-dioxins to hepatic cytosol from rat, mouse, guinea pig and hamster were determined using [3H]- 2,3,7,8-tetrachlorodibenzo-p-dioxin ...
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(Texas A&M University. Libraries, 1987)A reliable technique for extraction of brodifacoum (BDF) from serum using ether and ether:acetonitrile [1:1] was developed. Two HPLC systems (A: 1.5% Acetic acid, pH 4.5:acetonitrile [1:2] with 1% dibutylamine and B: 0.2 ...
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(Texas A&M University. Libraries, 1994)Cellular component-specific fluorescent probes were employed in laser cytometric assays of clonal rat liver and (Clone 9) and granuloma cells (SIGC) to evaluate mechanisms of toxicity caused by the common foodborne mycotoxins ...
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(Texas A&M University. Libraries, 1992)Aflatoxins encompass a structurally similar group of naturally occurring, fungal-elaborated poisons that have been strongly implicated in disease and death in men and animals. Consequently, there is a growing awareness of ...
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(Texas A&M University. Libraries, 1990)The metabolism of xanthotoxin, a naturally-occurring furanocoumarin photosensitizer, was studied in laying hens and lactating goats treated with a single oral dose equivalent to 10 mg xanthotoxin/kg of body weight. Within ...
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(Texas A&M University. Libraries, 1987)The effects of various halogenated hydrocarbon pollutants on hepatic microsomal drug and steroid metabolizing enzymes were determined in neonatal, immature and adult Long Evans rats. The teratogenic and/or fetotoxic effects ...
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(Texas A&M University. Libraries, 1988)Steroidal saponins were isolated from the alcoholic extracts of kleingrass (Panicum coloratum L.). Their aglycones, or sapogenins, were identified as diosgenin and yamogenin using TLC, melting point analysis and ER ...
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(Texas A&M University. Libraries, 1992)The role of the aryl hydrocarbon (Ah) receptor in mediating the immunotoxic effects of several polychlorinated diphenyl ethers (PCDEs), polychlorinated biphenyls (PCBs), and alkyl-substituted polychlorinated dibenzofurans ...
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(Texas A&M University. Libraries, 1990)2,3,7,8-Tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) and related compounds elicit a broad range of biochemical and toxic responses. One aspect of this dissertation was to assess the utility of an in vitro induction bioassay ...
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(Texas A&M University. Libraries, 1995)in most aquatic environments. Direct consumption and
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(Texas A&M University. Libraries, 1987)Hymenoxys odorata (bitterweed) is an economically important poisonous range plant indigenous to the southwestern United States. The sesquiterpene lactone (SL), hymenoxon, has been isolated from bitterweed and demonstrated ...
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(Texas A&M University. Libraries, 1994)Organophosphorus hydrolase (OPH) from P seudom onas diminuta MG is capable o f hydrolyzin g various organophosphorus com pounds. The structure-function relationship o f OPH was investigated utilizing a variety o f substrates ...
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(Texas A&M University. Libraries, 1994)Benzo(a)pyrene (BaP) elicits a diverse spectrum of toxic and biochemical responses in different species, i.e. cytotoxicity, immunotoxicity, mutagenicity, carcinogenicity, and atherogenicity. Previous studies have been shown ...
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(Texas A&M University. Libraries, 1995)2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) elicits a diverse spectrum of toxic responses that appear to be mediated through the aryl hydrocarbon receptor (AhR). TCDD also exhibits antiestrogenic activity in both the female ...