Browsing by Subject "DNA replication"
Now showing items 1-6 of 6
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(1985)I have studied the maintenance of methyl groups at the HpaII sites of autonomously functioning DNA upon transformation into mammalian cells. DNA molecules, containing the SV40 origin, were methylated in vitro with the ...
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(2015-05-05)DNA replication is a vital process to duplicate genetic material for inheritance. A conventional mitotic cell cycle is composed of G1, S, G2 and M phases, and DNA is replicated during S phase. Besides the conventional cell ...
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(2022-06-07)As a prototypic ciliated protozoan, Tetrahymena thermophila harbors two functionally and physically distinct nuclei within a shared cytoplasm. During the vegetative phase of the life cycle, the S phases of the diploid ...
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Isolation and genetic dissection of an eukaryotic replicon that supports autonomous DNA replication (Texas A&M University, 2007-04-25)Maintenance of genome integrity requires that chromosomes be accurately and faithfully replicated. We are using Tetrahymena thermophila as a model system for studying the initiation and regulation of eukaryotic DNA ...
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(2016-12-08)Bacteria precisely coordinate DNA replication and chromosome segregation with cell division; accurate regulation of each of these processes is critical to genome inheritance and thus reproductive success. During fast growth, ...
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(2014-02-06)As the nucleating protein for pre-replicative complex (pre-RC) assembly, the conserved Origin Recognition Complex (ORC) specifies where replication initiates in eukaryotic chromosomes. During the vegetative cell cycle of ...