Browsing by Subject "DNA damage"
Now showing items 1-7 of 7
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(Texas A&M University, 2004-11-15)Cave (Petrochelidon fulva) and cliff swallows (Petrochelidon pyrrhonota) were collected along the Rio Grande and evaluated as potential indicators of environmental contamination. The Rio Grande receives toxic substances ...
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(2012-07-16)Nanoparticles, while included in a growing number of consumer products, may pose risks to human health due to heavy metal leaching and/or the production of reactive oxygen species following exposures. Subcellular mechanisms ...
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(2014-05-06)p27 is a critical CDK inhibitor involved in cell cycle regulation, but its response to DNA damage remains unclear. Constitutive photomorphogenesis 1 (COP1), a p53- targeting E3 ubiquitin ligase, is downregulated by DNA ...
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(2017-04-28)Telomeres are specialized nucleoprotein caps at the end of linear chromosomes, critical for genome stability. A major function of telomeres is to distinguish chromosome ends from ends of double strand breaks. A second ...
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(2023-01-20)Atrial Fibrillation (AF) is the most common cardiac arrhythmia with a 1 in 4 lifetime risk. AF impairs cardiac function and increases the risk of thrombi, heart attack, and stroke. Although common and harmful, little is ...
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(2013-09-11)The ends of chormosomes are capped by telomeres, which distinguish the termini from damaged DNA. Paradoxically, DNA repair proteins are also required for telomere maintenance. How DNA repair pathways are regulated to ...
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(2010-08-26)Singleminded-2s (Sim2s) is a member of the basic helix-loop-helix Per-Arnt-Sim (bHLH-PAS) family of transcription factors. Members of this family play important roles in sensing and responding to environmental changes, ...