Browsing by Department "Biomedical Engineering"
Now showing items 1-20 of 391
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(2014-04-01)Breast cancer is the second leading cause of cancer death among females in the United States. Magnetic resonance imaging (MRI) has emerged as a powerful tool for detecting and evaluating the disease, with notable advantages ...
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Epithelial cells line surfaces of the human body. Since they define the boundary between internal and external environments, these cells maintain a polarity, created by localizing proteins at opposite ends of each cell, ...
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(2020-02-26)Vascular diseases, such as atherosclerosis and thrombosis, are the leading cause of morbidity and mortality worldwide. Despite major advancements to develop therapeutic interventions, the pathophysiology as it applies to ...
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A Microfluidic Model to Study Host-Microbiota Interactions in the Colorectal Tumor Microenvironemnt (2022-11-29)The colonic microbiota has been identified as a key player in the development of colorectal cancer. While changes in microbiota composition and function correlate with disease progression and treatment outcome, the mechanism ...
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(2023-05-01)Advancements in fluorescence intensity-based, fully injectable biosensors for continuous glucose monitoring for diabetes management has shown great promise over the past several years. Our group has extensively reported ...
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(2018-05-03)Spanins are required for the last step in bacteriophage lysis: the disruption of the outer membrane. However, bioinformatic analysis has shown 15 percent of phages lack a spanin gene, which suggests an alternate mechanism ...
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A Subject-Specific Biomechanical Modeling Approach to Understanding Sex Differences in Neck Strength (2023-05-16)Neck pain and injury are highly prevalent conditions that constitute a growing global healthcare burden. Females are at greater risk of neck injury from impact, are more likely to have persistent neck pain, and have poorer ...
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(2019-05-15)Bleeding and thrombosis episodes in children are often encountered during ECMO/VAD. Pediatric patients on ECMO are known to have compromised platelet function and depleted plasma factors, making them susceptible to bleeding ...
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(2013-09-24)Continuous-flow left-ventricular assist device (LVAD) implantation leads to increased peripheral resistance and development of arteriovenous malformations. These comorbidities have resisted mechanistic explanation, because ...
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(2020-03-16)In brain cancer surgery, it is critical to achieve extensive tumor resection without compromising adjacent healthy brain tissue. Various technologies (e.g. intraoperative magnetic resonance imaging and computed tomography) ...
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(2014-05-16)With significant progress made in the design and instrumentation of optical imaging systems, it is now possible to perform high-resolution tissue imaging in near real-time. The prohibitively large amount of data obtained ...
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(Texas A&M University, 2006-10-30)Muscular dystrophy is a disease characterized by skeletal muscle weakness and wasting, but little is known of alterations in the vascular system that occur with this disease. The culprit in many muscular dystrophies is a ...
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(2016-12-05)Tripping is responsible for a large percentage of falls. Minimum toe clearance (MTC) during the swing phase of gait is commonly used to infer the probability of tripping (POT). However, there is limited empirical evidence ...
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(2014-12-04)The protein resistance, subsequent thromboresistance, and marine anti-biofouling ability of poly(ethylene oxide) (PEO) was enhanced by the addition of a flexible, hydrophobic siloxane tether which imparts configurational ...
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(2014-09-05)Development of sensors for detection of various chemical and biological species is an important and ever-growing field. In particular, optical-based sensors enable a remote, rapid method for continuous or on-demand monitoring. ...
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Currently, research is being conducted on single tone sound transduction within the auditory portion of the inner ear, the cochlea [1]. The study of cochlear mechanics in large rodents has provided important insight into ...
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(2012-09-21)The use of parallel imaging techniques for image acceleration is now common in clinical magnetic resonance imaging (MRI). There has been limited work, however, in translating the parallel imaging techniques to routine ...
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(2009-05-15)Arterial wall morphology depends strongly on the hemodynamic environment experienced in vivo. The mammalian heart pumps blood through rhythmic contractions forcing blood vessels to undergo cyclic, mechanical stimulation ...
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(2019-11-13)Therapeutic cell delivery is a major strategy to stimulate the repair in tissue engineering and regenerative medicine. Efficacious cell therapies require a biomaterial carrier to retain injected cells in degenerated sites ...
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(2022-06-23)Poly(ethylene glycol) (PEG) is a blank-slate biomaterial that is commonly used in pharmaceuticals, drug delivery, and tissue regeneration applications. However, there are growing concerns about PEG immunogenicity, and it ...