Browsing by Author "Suchodolski, Jan S"
Now showing items 1-20 of 24
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Lagutchik, Stephen Christopher (2014-04-22)Cholecystokinin (CCK) is an important neuroendocrine peptide in the gastrointestinal tract, being the major stimulant for exocrine pancreatic secretion and gall bladder contraction. As such, cholecystokinin release may be ...
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Yamkate, Punyamanee (2021-10-12)Copper is an essential trace element that can produce reactive oxygen species (ROS). Excess ROS promote oxidative stress, which can lead to hepatic injury. Copper-associated hepatopathy is well-studied in humans and dogs. ...
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Bile Acid Metabolism and Gastrointestinal Microbiota in Dogs with Chronic Inflammatory Enteropathy Giaretta, Paula Roberta (2019-04-04)Chronic inflammatory enteropathy (CIE) is a common cause of gastrointestinal signs in dogs, but its etiology is poorly understood. Dogs with CIE have imbalances in their bile acid (BA) metabolism and gastrointestinal ...
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Lidbury, Jonathan Andrew (2015-11-13)Chronic hepatitis is an important disease in dogs that can lead to hepatic fibrosis, portal hypertension, and hepatic encephalopathy. Histological assessment of liver biopsy specimens is currently required to definitively ...
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Pfent, Catherine Marie (2015-11-02)Controlling metastatic and invasive tumors is the challenging part of treating cancer. The overall aim of this dissertation was to target these aggressive cells, called tumor-initiating cells (TICs). They exploit embryonic ...
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Grützner, Niels (2013-12-11)In recent history, no other dog breed has grown in popularity and/or population size in such a short period of time as is the case for the Chinese Shar Pei in North America. After being introduced to North America in the ...
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Bridges, Cory Seth (2017-01-04)Ferrets are valuable animal models for the study of many human diseases. Cystic fibrosis (CF) and pancreatitis are two such human diseases that could benefit from a ferret model. The pancreatic disease processes that occur ...
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Suchodolski, Jan S; Dowd, Scot E; Westermarck, Elias; Steiner, Jörg M; Wolcott, Randy D; Spillmann, Thomas; Harmoinen, Jaana A (BMC Microbiology, 2009)
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Arnold, Carolyn Elizabeth (2020-11-04)The microbiome of the equine gastrointestinal tract (GIT) form a symbiotic relationship with the horse, and play a critical role in nutrition, metabolism, and immunity. This work utilized 16S rRNA sequencing and metabolomics ...
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Heilmann, Romy Monika (2015-04-24)Inflammatory bowel disease (IBD) is a common condition in dogs that is challenging to diagnose. A dysregulated innate immunity plays a major role in its pathogenesis, and surrogate inflammatory markers that reflect disease ...
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Marsilio, Sina (2019-05-23)Feline chronic enteropathy is a very common disorder with an increasing prevalence over the past decades. It mainly comprises idiopathic inflammatory bowel disease (IBD) and alimentary small cell lymphoma (SCL). Histopathology, ...
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Hang, Ingrid; Heilmann, Romy M; Grützner, Niels; Suchodolski, Jan S; Steiner, Jörg M; Atroshi, Faik; Sankari, Satu; Kettunen, Anu; de Vos, Willem M; Zentek, Jürgen; Spillmann, Thomas (BMC Veterinary Research, 2013)
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Ishii Miyagawa, Patricia Eri (2022-07-25)Dogs with chronic clinical signs of gastrointestinal disease such as diarrhea, vomiting, weight loss, and/or loss of appetite are often diagnosed with chronic enteropathy after infectious, parasitic, neoplasia, and ...
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Guard, Blake Crosby (2017-06-23)Chronic gastrointestinal disease in dogs can manifest itself in many different ways including vomiting, diarrhea, and weight loss. Bile acid dysmetabolism has recently been recognized as an important component of chronic ...
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Honneffer, Julia Beth (2017-05-30)The canine gastrointestinal tract (GIT) is home to a complex ecosystem known as the microbiome. The microbiota (i.e., bacteria, viruses, fungi, and protozoa) are metabolically active, augmenting host digestion and thereby ...
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Lawrence, Yuri Alexander (2019-02-28)Chronic hepatitis can present a diagnostic challenge, with different types of chronic hepatic disease being associated with similar clinical and laboratory findings. Clinical signs of chronic hepatitis are often non-specific; ...
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Xenoulis, Panagiotis G; Cammarata, Paul J; Walzem, Rosemary L; Macfarlane, Ronald D; Suchodolski, Jan S; Steiner, Jörg M (BMC Veterinary Research, 2013)
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Kim, Hye Mee (2013-12-11)Ulcerative colitis is a chronic inflammation of the large intestine, and it may increase risk of human colorectal cancer. Polyphenolics from mango and pomegranate have been shown to have potent anti-inflammatory properties, ...
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Gart, Elena Vladimirovna (2017-04-24)Salmonella enterica serovar Typhymurium (S. Typhimurium) is a bacterial pathogen which is a cause of over a million cases of gastrointestinal illness worldwide. The GI tract is a large and complex environment influenced ...
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Semiparametric Analysis of Complex Polygenic Gene-Environment Interactions in Case-Control Studies Asher, Alexander Allen (2018-08-07)Gene-environment interactions can be efficiently estimated in case-control data by existing retrospective methods that assume gene-environment independence in the source population, but such techniques require parametric ...