Browsing by Author "Li, Qinglei"
Now showing items 1-12 of 12
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Qin, Yushu (2023-05-09)Abnormal placenta development has been recognized in pre-eclampsia (PE) and gestational diabetes (GDM), which are both leading causes of maternal death during pregnancy. GDM is recognized as a risk factor for PE. Peroxisome ...
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Grady, Sicilia Tatiana (2017-06-09)Aging affects the reproductive efficiency of females. In rodent models, injection of mesenchymal stem cells (MSCs) improves function and induces trophic mRNA expression in ovaries compromised by chemotherapy. However, ...
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Wang, Xiaoqiu (2015-12-18)The greatest limitation to reproductive performance in most mammals, including humans, is embryonic mortality, which, in general, claims 20%-40% of the embryos during the peri-implantation period of pregnancy. During that ...
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Peng, Jia; Li, Qinglei; Wigglesworth, Karen; Rangarajan, Adithya; Kattamuri, Chandramohan; Peterson, Randall; Eppig, John; Thompson, Thomas; Matzuk, Martin (Proceedings of the National Academy of Sciences of the United States of America, 2013)
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Krishnaveni Sivakumar, Kirthiram (2018-07-31)Environmental exposure to endocrine-disrupting chemicals (EDCs) is one of the causes of premature ovarian failure (POF). Hexavalent chromium (CrVI) is a heavy metal EDC widely used in more than 50 industries, including ...
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Karki, Keshav Bahadur (2019-11-05)Specificity protein transcription factors (Sp1, Sp3 and, Sp4) and members of the orphan nuclear receptor 4A subfamily (NR4A1, NR4A2 and, NR4A3) are highly expressed in most solid tumors and their derived cell lines compared ...
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Zhang, Lei (2023-08-04)NR4A subfamily is a group of orphan nuclear receptors with no known endogenous ligands and includes three members: NR4A1, NR4A2, and NR4A3. NR4A members play important roles in maintaining cellular hemostasis and are ...
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Roach, Alexis Nicole (2023-08-02)This dissertation utilizes a mouse model to investigate how paternal alcohol consumption affects in vitro fertilization (IVF) success, assisted reproductive technology (ART) fetoplacental development, the transcriptional ...
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Burns, Gregory Willis (2013-11-21)After 40 years of research, in vitro systems for mammalian embryo production produce lower quality embryos than those derived from in vivo sources. Recent reports have demonstrated that in vitro bovine oocyte maturation ...
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Ni, Nan (2022-07-04)Mechanisms governing the female reproductive tract development and function are incompletely defined. Transforming growth factor β (TGFβ) superfamily signaling regulates multifaceted reproductive processes. TGFβ ligands ...
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Gao, Yang (2017-07-14)Transforming growth factor beta (TGFβ) superfamily signaling regulates multiple reproductive events. However, the in vivo role of the TGFβ signaling in uterine development and function is not well defined. Conditional ...
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Fang, Xin (2022-07-25)Reproductive development and tumorigenesis are the two main topics in reproductive research. Enhancer of zeste (EZH2), a core component of Polycomb Repressive Complexes 2, possesses histone methyltransferase activity that ...