Browsing by Author "Kladde, Michael"
Now showing items 1-9 of 9
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Cargill, Holly Beth (Texas A&M University, 2006-08-16)Most proteins residing in the mitochondrial matrix are synthesized in the cytosol and post-translationally imported into the mitochondrial matrix. The matrix-targeted preproteins traverse the outer mitochondrial membrane ...
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Jessen, Walter Joseph (Texas A&M University, 2006-04-12)In eukaryotes, the organization of DNA into chromatin is a primary determinant of gene expression. Positioned nucleosomes in promoter regions are frequently found to regulate gene expression by obstructing the accessibility ...
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Han, Bong Kwan (Texas A&M University, 2007-04-25)How proliferating cells maintain the copy number and overall size of their organelles is not clear. In the budding yeast Saccharomyces cerevisiae the G1 cyclins Cln1,2,3p control initiation of cell division by regulating ...
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McCormick, Peter Joseph (Texas A&M University, 2005-02-17)During co-translational integration, the transmembrane (TM) sequence of a nascent membrane protein moves laterally into the ER lipid bilayer upon reaching the translocon. Our lab has previously shown that this movement ...
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Neef, Daniel Wilhelm (Texas A&M University, 2005-11-01)To ensure a continuous supply of phosphate, living organisms have devised complex mechanisms to regulate the uptake and subsequent utilization of this essential nutrient. An important aspect of phosphate metabolism is the ...
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Dhasarathy, Archana; Kladde, Michael (Molecular and Cellular Biology, 2005)
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Kuo, Mack Ryan (2009-05-15)Malaria and tuberculosis constitute two of the world’s deadliest infectious diseases. Together, they afflict over one third of the world’s population. Once thought of as one of a group of nearly vanquished diseases only ...
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Carvin, Christopher Dumas (Texas A&M University, 2005-08-29)Regulation of gene expression is vital for proper growth and prevention of disease states. In eukaryotes this regulation occurs in the context of chromatin which creates an inherent barrier for the binding of trans-acting ...
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Langlais, Carrie-Lynn (2009-05-15)Most bacteriophage escape the confines of the host bacterium by compromising the integrity of its cell wall, an event that results in rupture (lysis) of the cell. The lysis strategy of bacteriophage Qβ is inhibition of ...